In order for your brain to function effectively, it’s important that new connections are being formed. If you’d like to improve your learning capacity and memory, Uridine may be the perfect nootropic solution for you. Not only can you boost cognitive functioning, but you can improve your overall health and wellness.
It has been found that when there’s low levels of Uridine in the brain, memory formation can become impaired. This can also lead to a decline in brain plasticity. Although you can consume Uridine within your diet, supplementation can aid in significant changes to your mood and memory.
What Exactly Is Uridine?
Uridine is a substance which is naturally occurring in the liver. It contains both a pyrimidine base, as well as a nucleic acid. Due to these components, Uridine is known to be a nucleoside. In order to understand its importance; Uridine is one of the four basic components of RNA.
When storing memories within your brain, it requires large amounts of RNA. By taking Uridine supplements, you can increase RNA levels; improving memory formation, as well as retention performance.
Since Uridine is so receptive to additional phosphate groups, it can also create one of three other nucleotides. These are used to regulate one’s metabolism. Research has shown, that Uridine works well with choline. The effects of these two substances, creates nootropic benefits. Additional research is exploring its ability to work with fatty acids, in order to act as an anti-depressant.
How Does Uridine Work?
The key regarding Uridine’s method of action, is the way in which it increases brain Phosphatidylcholine production. This brain chemical is known to assist the operation of cells, while regulating various enzymes within the brain.
It is also known to increase the production of neurites, which leads to greater plasticity of the brain. This aids in both encoding and storage in regards to memory. A neurite is simply a projection for a neuron, such as an axon or dendrite. In turn, this helps to form synapses within other areas of the brain.
While focusing on the structure and function of the brain, it is highly complex. There are billions and billions of neurons, which create an intricate network of connections. These connections are continually changing. Within recent research, it’s been found that new memories are stored through long-term potentiation.
Long-term potentiation is when there’s an increase in synaptic strength, due to the stimulation of a chemical synapse. In terms of new memories, this process has been linked to new connections being formed between neurons. When you have more Uridine within your body, this leads to higher rates of synaptogenesis. The result is greater memory retention and greater cognitive ability.
Uridine also works by boosting dopamine levels in the brain. Dopamine is a neurotransmitter, which influences our mood and motivation. It also plays a role in the pleasure center of the brain. While focusing on cognition, dopamine influences our ability to focus and maintain attention.
Uridine not only increases dopamine levels, but it is also converted into CDP choline within the brain. This is also known as Citicoline, which increases acetylcholine synthesis. Acetylcholine is also a neurotransmitter, but it is more closely linked to memory; as well as focus, information processing, and brain plasticity.
What Are the Key Benefits of Uridine?
When you begin taking any new supplement, you will want to know if it is worth taking. How can it help you? Well, Uridine provides some highly extensive benefits. Not only can it aid in working memory, but also fluid intelligence. When you improve your fluid intelligence, you’re able to problem solve in novel situations more effectively.
The reasons behind Uridine’s benefits, is highly reliant on the conversion of Uridine into choline, which then converts into acetylcholine. It is believed that due to these mechanisms of action, one can also slow down the aging process of their brain. This is why Uridine is showing promise regarding preventative measures against degenerative conditions, such as Alzheimer’s.
Based on Uridine’s influence on dopamine, users often experience a better mood and higher levels of motivation. This includes the ability to manage stress, symptoms of anxiety, as well as symptoms of OCD. It is also believed to improve the health of brain cells, aiding in lipid membranes. To amplify the effects of Uridine, it’s recommended that you stack this supplement with choline directly.
What Are the Potential Side-Effects?
Just as you focus on the benefits of a supplement, you should also familiarize yourself with potential side-effects. Uridine is considered to be extremely safe, as majority of people tolerate this supplement well. Considering Uridine can be found naturally in foods such as broccoli and tomatoes, you would expect it to be safe.
With all supplements, you need to pay attention to the recommended dosage. The only side-effects that may occur, are fatigue, headaches, nervousness, as well as potential gastrointestinal distress. It is also believed that this supplement may reduce levels of vitamin B12.
To combat this issue, it is suggested that you take B-complex vitamins daily. Not only will this help maintain levels of B12, but B-vitamins also improve overall brain health and function. Many are deficient in
What Is the Recommended Dosage of Uridine?
You can take Uridine alone, however, this supplement is generally taken in a stack. It is recommended that you take between 500 mg and 2 grams daily. For those that are looking for nootropic effects, generally take on average, 1 gram daily. It is also highly recommended that you take Uridine with a high quality choline source. This will maximize results.
Based on all the nootropics available on the market, Uridine is one of the few that is an absolute must-have. This supplement is especially important for the older population, as well as anyone whom is taking part in an anti-aging regimen. Not only does it influence fluid intelligence and memory, but it allows neurons to become more plastic; benefiting any user.