What are Anxiolytics?

Anxiolytics are supplements, medications, or any other intervention that reduces the effects of anxiety. Anxiety can be crippling, as it can make everyday life challenging. There are many aids out there for anyone suffering from anxiety.

When it comes to the nootropics community, anxiolytic medications that enhance cognitive functions are the main focus. There are three popular anxiolytic supplements  on the market that aid in cognitive abilities and memory function. These three supplements are; Sulbutiamine, Phenibut, and L-Theanine. Although not all of these directly enhance cognitive functioning, they’re often used in a stack as they yield some great benefits.

How Do Anxiolytic Drugs Work?

When someone is highly anxious, there’s two routes that can be taken. You can attempt to suppress the anxiety through sedation, or you can work to increase neurotransmitters that improve one’s mood, cognitive function, and perception.


This neurotransmitter is purely anxiolytic. When you increase levels of GABA, the effects of anxiety can be greatly reduced. This neurotransmitter is an inhibitor, which is the same neurotransmitters active when you consume alcohol or take benzodiazepines.

Although GABA supplements are great to calm users down, they tend to have negative effects on cognition. Phenibut for instance, is not technically a nootropic. Piracetam is derived from GABA’s structure, but does not yield GABAeric effects.


This neurotransmitter plays a large role in our mood, appetite, social behaviour, and some aspects of cognitive functioning. It is not inhibiting like GABA is, but there is more certainly a connection regarding anxiety and serotonin levels. Serotonin can also affect nootropic benefits, as mood and memory are improved.

Three Beneficial Anxiolytics

In order to better understand the three supplements mentioned above, let’s take a closer look. What benefits do they yield? How do they improve cognitive function? Are there any concerning side-effects?


Sulbutiamine is a version of thiamine, also known as vitamin B1. This is an essential vitamin in terms of nootropics, and Sulbutiamine mimics its effects more effectively. Thiamine cannot cross the blood-brain barrier, but Sulbutiamine can. This anxiolytic can be taken on its own, or taken in a stack to produce some great benefits.

Thiamine is essential when synthesizing both GABA and Acetylcholine. As we know, Acetylcholine is essential for cognitive function. When there is an increase in this neurotransmitter, cognitive abilities are improved. Since Sulbutiamine works in the same fashion, it has a positive effect on both the cholinergic, glutamatergic, and dopamine systems.


This supplement is a derivative of the neurotransmitter GABA. Since GABA is known to produce highly calming effects, it’s not typically considered a nootropic neurotransmitter. Although some believe that Phenibut provides nootropics benefits, the evidence to support this is fairly limited. This supplement is generally taken in a stack, due to the mood enhancing properties it provides.

It is important to follow the recommended doses so that benefits are experienced, instead of negative effects. Phenibut provides numerous benefits including; increased relaxation, reduced anxiety and stress, improved mood, and sleep induction. As you can see, this is best taken in a stack alongside a racetam for instance.


You may be more familiar with L-Theanine than you think, as it is most commonly found in tea. Behind water, tea is the most consumed beverage across the globe. L-Theanine is actually an amino acid, which provides numerous benefits.

Since L-Theanine is considered an anxiolytic, it’s not surprising that it decreases stress levels. This calming effect is highly beneficial when administered in a stack. For example, L-Theanine and caffeine are typically taken in a stack. Not only does it relax users, but it also helps control mood, improve memory, and increase learning abilities.

Benefits of Anxiolytic Products: Phenibut

There are many benefits when taking a stack that contains an anxiolytic. Lets take a closer look at some of the core benefits of Phenibut for example.

  • Sleep: Some nootropics create issues with sleeping. Phenibut on the other hand, actually improves one’s sleep. The quality of sleep is improved, allowing the individual to feel relaxed and calm. This can be a great benefit when issues with sleep have been reported.
  • Mental Performance: Studies conducted on mice have shown that as concentrations of Phenibut are increased, reaction time significantly improves. This increase in mental performance allows for higher focus.
  • Feelings of Well-Being: Since dopamine levels are stimulated at low levels, users feel more motivated and are able to regulate their pleasure-pain cycle more effectively.

Anxiolytic Stacks

Since most anxiolytic supplements do not greatly affect cognition, they’re generally taken in a stack. If you’d like to decrease your levels of anxiety, these supplements are a great option. The effectiveness of these stacks will depend on the origin of your anxiety. If you have a chemical imbalance, then increasing neurotransmitters (serotonin, GABA) can help to reduce these feelings.

If you’re looking to achieve this effect, try taking an anxiolytic supplement with your racetam intake. Aniracetam itself has some anxiolytic effects, targeting selective serotonin receptors. L-Theanine acts both as a nootropic and calming supplement. It does not create sedation, which is why it is used by many. L-Theanine is often stacked with caffeine to create high levels of cognitive functioning, while eliminating any negative effects associated with caffeine jitters.

Ready to Buy Anxiolytics Online?

If you’re ready to try anxiolytic supplements for yourself,  we have you covered. At Nootropics Info, we have the best places to buy anxiolytics online. Don’t waste your time at the mall when you could be shopping from anywhere as long as you have an internet connection. Tired of anxiety controlling your life? Order anxiolytic supplements and see for yourself whether or not they help you personally. This is the best way to see if they’re going to assist with your anxiety in a safe and effective way.